Sunvox alex zolotov7/8/2023 ![]() Pathological raphe signal was observed mainly in patients suffering from daytime sleepiness (sensitivity = 42.1 %, specificity = 88.9 %, p = 0,044), while alterations did not correlate with symptoms of depression. Width of third ventricle was significantly larger in the patient group ( p = 0.021) and correlated with MRI-based volumetry ( R 2 = 0.756). Mesencephalic raphe was hypoechogenic in nine (29 %) DM-patients and was more frequently in DM1 patients ( p = 0.021). Nine patients (29 %) showed hyperechogenicity of substantia nigra. Ventricle diameters were additionally compared to 3T-MRI volumetry. TCS abnormalities were correlated to clinical findings and secondly compared to 31 controls. Echogenicities of basal ganglia and mesencephalic regions were assessed according to the examination protocol for extrapyramidal disorders using a Toshiba Aplio ® XG ultrasound system. Thirty-one DM-patients (DM1 = 17 DM2 = 14) were examined clinically and sonographically by independent physicians. The aim of this study was to evaluate TCS-findings in DM-patients in correlation with their clinical status. Ial sonography (TCS) has become a reliable diagnostic tool in the evaluation of several CNS disorders. CNS involvement is one important aspect of both, myotonic dystrophy type 1 and type 2 (DM1, DM2). Myotonic dystrophies (DMs) are clinically similar but distinct multisystemic diseases related to different repeat expansion mutations.
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